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Opana (Oxymorphone) ER 40mg

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Opana (Oxymorphone) ER 40mg

Oxymorphone, sold under the brand names Numorphan among others, is a powerful semi-synthetic opioid analgesic (painkiller) Whether in a dedicated pain-management clinic or in a community pharmacy, pharmacists can provide valuable education and treatment recommendations to patients and clinicians. Pain programs, jointly managed by pharmacists, nurse practitioners, specialists in behavioral medicine and functional restoration, and specialty pain physicians, can enhance the satisfaction of patients and health care professionals, improve clinical outcomes, and minimize the need for secondary pain referrals.1 Pharmacists who become knowledgeable in pain pharmacopoeia can facilitate safe, effective, and cost-beneficial equianalgesic opioid conversions in primary care settings

  • Description
  • Reviews (7)

Description

Differences among opioid influence individual patient response and tolerability, risks and benefits in specific disease states, the likelihood of drug interactions, and ease of monitoring. Differences among patients with respect to genetic factors, age, sex, and the prior use of opioid also contribute to variability of response to individual opioid6 Consequently, when selecting LA opioid, clinicians cannot reliably predict how a given patient will respond. Patients with chronic pain usually require consecutive trials of several LA opioid before they find one that provides adequate analgesia with acceptable tolerability.7–9For this reason, it is essential to have multiple LA opioid from which to choose.

PHARMACOLOGY AND PHARMACOKINETICS

Oxymorphone has selective affinity for the mu-opioid receptor, whereas oxycodone has weaker mu-receptor affinity and greater kappa-receptor affinity. Oxymorphone has lower protein binding (10% to 12%) compared with morphine (30% to 35%) or oxycodone (45%).Its highly lipophilic properties facilitate its transit across the blood–brain barrier.

Although oxymorphone ER has minimal potential for pharmacokinetic interactions, its use with sedatives, tranquilizers, hypnotics, phenothiazines, and other central nervous system (CNS) depressants can produce additive effects. Hence, as with other opioids, vigilance is required in preventing pharmacodynamic interactions during therapy with oxymorphone ER.

Pharmacists can help prevent medication errors, particularly those that result in drug interactions. Patients receiving opioid therapy for chronic pain may have complex medical problems, often requiring the involvement of their primary care physician, a pain specialist, and one or more medical or surgical s

CLINICAL TRIAL PROGRAM

The clinical trial program for oxymorphone ER has included more than 2,000 opioid-naive and opioid-experienced patients with chronic cancer pain and non-cancer pain. The duration of treatment ranged from two weeks to two years. Collectively, the trials demonstrated that oxymorphone ER was an effective, generally well-tolerated 12-hour opioid agent in controlling chronic pain.

7 reviews for Opana (Oxymorphone) ER 40mg

  1. 5 out of 5

    C’est ma quatrième commande que j’ai reçue aujourd’hui. Ce magasin en vaut vraiment la peine. Je vais le recommander à tous mes amis. J’ai la preuve .

    Armand

  2. 5 out of 5

    Le “Opana (Oxymorphone) ER 40 mg” reçu ce matin est de grande qualité et ravi de ce succès. Je ferai plus de commande demain et aussi, je suis sûr que certains de mes amis passeront également leur commande.
    George

  3. 5 out of 5

    Thanks for the order , got mine today and so pleased with the quality .

    Jorge

  4. 5 out of 5

    Really pleased with the Oxymorphone, is of high purity , the delivery was also fast. Never expected i could make such payment with bitcoin .

    Basil

  5. 5 out of 5

    Really so grateful with the quality of the product i got here .

    Thanks for the order .

    Mike

  6. 5 out of 5

    So pleased with the order , do really appreciate the quality .

    Thanks ,

    Walter

  7. 5 out of 5

    Thanks for the order and so pleased with the quality , one of the best ever had here online .

    Kim


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